1. What is a Stem Cell?
Stem cells are mother cells that have the potential to duplicate themselves endlessly and become virtually any type of cell, tissue, or organ in the body. One of the main characteristics of stem cells is their ability to self-renew, or multiply, while maintaining the potential to develop into other types of cells. Stem cells can become cells of the blood, heart, bones, skin, muscles, brain etc. There are different sources of stem cells, but all types of stem cells have the same capacity to develop into multiple types of cells. The best known type of pluripotent stem cell is the one present in embryos and form at the blastocyst stage of development. This helps babies grow within the womb.
Fetal stem cells: Obtained from the tissues of a developing human fetus, and some characteristics of the tissues they are taken from. For example, those taken from fetal muscles can make only muscle cells. These are also called progenitor cells.
Adult stem cells: Obtained from the tissues of the adult body. The most common is the marrow, which is a rich source of stem cells. stemcells.nih.gov/info/Regenerative_Medicine/pages/2006chapter2.
1. What is a Stem Cell?
Stem cells are mother cells that have the potential to duplicate themselves endlessly and become virtually any type of cell, tissue, or organ in the body. One of the main characteristics of stem cells is their ability to self-renew, or multiply, while maintaining the potential to develop into other types of cells. Stem cells can become cells of the blood, heart, bones, skin, muscles, brain etc. There are different sources of stem cells, but all types of stem cells have the same capacity to develop into multiple types of cells.
The best known type of pluripotent stem cell is the one present in embryos and form at the blastocyst stage of development. This helps babies grow within the womb.
Fetal stem cells:
Obtained from the tissues of a developing human fetus, and some characteristics of the tissues they are taken from. For example, those taken from fetal muscles can make only muscle cells. These are also called progenitor cells.
Adult stem cells: Obtained from the tissues of the adult body. The most common is the marrow, which is a rich source of stem cells.
2. What is the Stem Cell Theory of Aging?
The stem cell theory of aging postulates that the aging process is the result of the inability of various types of stem cells to continue replenishing the tissues of an organism that have functionally differentiated cells that are capable of maintaining that tissue’s (or organ’s) original function. Damage and error-accumulation in genetic material are always a problem for systems, regardless of their age. The number of stem cells in young person is much higher compared to older people. This causes a better and more efficient replacement mechanism in the young contrary to the old. In other words, aging is not a matter of the increase in damage. Rather, it is a of failure to replace the damage due to a decreased number of stem cells.
Stem cells decrease in number, and tend to lose the ability to differentiate into progenies (lymphoid lineages), and myeloid lineages.
Maintaining the dynamic balance of stem cell pools requires several conditions. Balancing of proliferation and quiescence, along with homing (See niche) and self-renewal of hematopoietic stem cells, are favoring elements in the maintanance of stem cell pools, while differentiation, mobilization and senescence are detrimental. These detrimental effects will eventually cause apoptosis.
Self-renewal is the process by which stem cell divide to make more stem cells, thereby perpetuating the stem cell pool throughout life. Self-renewal is division along with maintenance of the undifferentiated state. This requires cell cycle control and regular maintenance of multipotency or pluripotency, depending upon the stem cell.
When an organ goes through a process that requires renewal, such as the natural aging process, this organ releases substances that trigger the release of stem cells from the bone marrow. These released stem cells then follow key substances, and the migration starts in the blood until they reach the organ in need, where they proliferate and differentiate into cells of this organ, supporting the natural process of renewal.
3. Do NuVi Global products use any type of Stem Cells in their supplements?
NuVi Global products do not use stem cells in any of our products. StemForte® was formulated with 24 herbal, fruits, colostrum etc, being al- natural ingredients and were combined synergistly.
4. What is the science behind StemForte® and what does it do?
StemForte® is a unique supplement made with 24 all-natural ingredient,s using a proprietary formula.
StemForte® nourishes the bone marrow through ideal nutrition, supporting the own body’s natural ability to produce an increased levels of circulating stem cells by stimulating the release, activity, and proliferation of stem cells. Shown in doubled-blind clinical studies, StemForte® has bene shown to increase the production of stem cells – the body’s system for the renewal process.
5. What is the recommended amount of StemForte® to take?
Thre capsules a day before or after meals is a good amount, although studies have concluded that six capsules is the optimum intake to promote the release of the body’s own stem cells.
6. Would my bone marrow stem cells be depleted using StemForte®?
Is there a finite number of bone marrow stem cells?
StemForte® contains nutritional ingredients. Scientists have long known that folic acid, Vitamin B12, and iron are required for bone marrow stem cells to differentiate into mature red blood cells. The formulation inside StemForte® gives the necessary nutrients, not only to nourish the bone marrow stem cells, but also gives the necessary ingredients to stimulate them to be released. And since bone marrow is contstantly producing millions of stem cells for an entire lifetime, they will be not depleted.
c. Craciunescu CN, Brown EC, Mar MH, et al. Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. J Nutr. 2004 Jan;134(1):162-6.
7. What is the healing crisis or Herxheimer effect?
When a health problem begins, generally the person affected does not feel any immediate discomfort because the body has compensation mechanisms that try to locate and combat the problem. If the person’s lifestyle does not change, and the same habits continue, the problem will get worse and discomfort will begin to appear. Symptoms will indicate that the organisms is not functioning properly, when the body gives off a signal that something is wrong. It is necessary to change the lifestyle, reather than masking the symptoms.
A symptom is a nature’s alarm. When a symptom arises, the underlying problem that is creating the symptom must be found and addressed through detoxification, along with a change in lifestyle. A person with health problems can lose weight at the beginning of a lifestyle change because the body has become free of large numbers of toxic and morbid substances that have accumulated over the years. These toxic and harmful substances are then evacuated from the organism, thanks to the purifying action of the body’s natural system. Therefore, as the person’s lifestyle changes, detoxification takes place, and person is often seen with more vigor, joy, and enthusiasm for life.
Some symptoms are part of the detoxification process, while others are due to the change in lifestyle. These changes are known as the “healing crisis”, or the Herxheimer Effect. Those who begin to consume natural substances and/or perform a detoxification may experience an apparent worsening of health, such as: fatigue, malaise, congestion, skin rashes, chills, diarrhea, muscle aches, among others. These disturbances are evidence of the organism trying to liberate itself of toxins, and is often known as a “crisis”. People who are unaware that a crisis could happen may assume that the detoxifying products are harmful, when in reality it is a positive thing to experience. The more toxins there are in a person’s system, the stronger the crisis of detox could be. When these sensations are experienced, it is important to drink plenty of filtered water to keep the body hydrated, which will help remove the toxins more rapidly. Drink herbal teas or vegetable juices on a regular basis and rest more than usual. Epson salt baths are also very helpful. Always consult your physician for any symptoms or illness you might have to avoid any misunderstanding of your symptoms and the healing crisis.
8. Are there side effects or healing crisis after starting StemForte®?
Some may occur if the body is highly toxic – high indican from very poor digestion or if you have taken lots of prescription drugs. This usually might occur if high doses of StemForte® are taken. If so, you may experience skin eruptions, rashes, digestive problems or flu-like symptoms when starting StemForte®. These usually disappear in a couple of days. Sometimes the growth factors in colostrum – a key ingredient in StemForte® – may create initial pain in areas of old wounds or injuries as they begin to heal. If dicomfort continues, decrease the dosage for a few days and then resume, slowly increasing the dosage as optimum levels are reached.
These detox symptoms are not otherwise noticeable if small doses are taken in the begining. It is important to note that each person’s body is different. For this reason, some people might experience this "crisis" even after taking small doses.
9. Can stem cells cause cancer?
Only embryonic stem cells have been associated with the development of abnormal growth. Stem cells that are present in specialized tissues, such as the intestinal mucosa, may also play a role in the development of an abnormal growth. However, stem cells that are released from the bone have not been associated with such problems.
Ccancer is caused by mutations to genes within a cell that lead to abnormal cell growth. Finding out what causes this genetic mutation has been the holy grail of medical science for decades.
10. What is the best way to take StemForte® capsules?
StemForte® can be taken with or without food. Some people with stomach discomfort can chose to take them after meals, rather than on an empty stomach.
11. Is StemForte FDA approved?
No. Dietary supplement manufacturers and distributors are not required to obtain approval from FDA before marketing dietary supplements. Before a firm markets a dietary supplement, the firm is responsible for ensuring that:
- The products it manufactures or distributes are safe
- Any claims made about the products are not false or misleading
FDA does regulate product quality, product safety, and product claims, and has authority to remove products from the market that are not safe, or that make claims that are not substantiated by scientific evidence.
12. Can StemForte cure any disease? And if I am taking medications should I discontinue them?
StemForte® helps your body to release more stem cells naturally, and should not replace your medications. Please look for the StemForte® disclaimer on the label – “These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease”.
13. Are there any synthetic ingredients in StemForte®?
StemForte® is made of 100% natural ingredients.
14. StemForte contains Colostrum, does it matter which colostrum brand you use?
Yes. Colostrum must not be processed by excessive heat because this will cause loss of most of its biological activity. Colostrum should come from cows that are “organic” – free of pesticides, hormones and antibiotic. The best colostrum comes from pasture-fed cows. Cows were meant to eat healthy, green grass – not dried, processed feed, corn or soybeans. Grass-fed cows produce much healthier colostrum with maximum natural immunity to harmful soil-based bacteria and other pathogens. Colostrum must be water-soluble for maximum absorption, and is done by making it micronized and homogenized. It is impossible to obtain water-soluble colostrum if it has been frozen.
It is virtually impossible to obtain a U.S. source of colostrum from pasture-fed cows that meet the above criteria. Even the organic herds in the U.S. are seldom pasture-fed.
Measures of quality and safety are taken throughout the stages of the food chain. Fertilizer suppliers to our colostrum vendor producers do not use dicyandiamide. Our vendorss suppliers do not accept feed that has been treated with pesticide or herbicide residues. Our colostrum vendors’ suppliers prohibit the use of estradiol and prolactin. All dairies that supply colostrum to our vendors certify that their cows are free from antibiotics, BSE, and hormones, such as rBGH, at the time of calving. Our vendor’s suppliers certify they do not add melamine or hydrolyzed leather protein to the raw colostrum. Our vendors do not accept irradiated colostrum. Nor do they perform colostrum irradiation – radionuclide levels specified by Codex, and are monitored in-house under a regulated control scheme.
Our colostrum powder does not contain levels of chemical contaminants, or residues that exceedthe limits specified by Codex.
Our colostrum vendors have the most sophisticated laboratory in the colostrum industry, and are registered with the United States Government. Our vendors; laboratory is staffed with eight scientists with bachelor’s degrees or higher. These laboratories test all incoming raw colostrum and finished colostrum products for quality and safety. There are over 100 laboratory standard operating procedures, and over 400 testing methods which include assays such as antibiotics, pathogens, allergens, melamine, and GMO testing. Intramural testing capabilities are expanding to include <1ppm Dicyandiamide (DCD), <0.5ppm sodium cyclamate, PAH, and complete pesticide and herbicide panel trace residue detection among many other assays that are currently submitted to third-party testing facilities.
Customers who want to procure organic colostrum should be advised that the commercial supply of certified organic colostrum is extremely small. In the U.S., if a product is promoted as “organic”, it MUST be Certified Organic under the U.S. National Organic Program. If a product is not certified, but is marketed with an organic claim, it is in violation of U.S. law.
Colostrum is collected from dairies that certify that their cows are free from antibiotics, BSE and hormones, such as rBGH, at the time of calving.
Colostrum is only collected from USDA Grade A dairies that are monitored daily for quality assurance compliance. Raw colostrum from each dairy undergoes a 42-point testing protocol including chemistry, speciation of pathogens and general microbiology, and other necessary testing to assure colostrum is collected from the first milking, and free from adulterants.
Complete pesticide and herbicide panel trace residue detection, among many other assays, are currently submitted to third-party testing facilities.
15.What if I am lactose-intolerant?
Lactose-intolerance is a food allergy that creates an imbalance in specific cytokines in the body. The proline-rich polypeptides, or PRPs, in colostrum normalize, or modulate, the levels of cytokines in the body so the body does not recognize the lactose as a food allergen.
Even though the amount of lactose in colostrum is small, it may cause some digestive discomfort if you are lactose intolerant.
Please consult your health care practitioner regarding any food allergies. If you experience discomfort after taking colostrum, one strategy is to reduce the amount you are taking and drink plenty of water. If discomfort persists, discontinue use and consult your health care practitioner.
16. What about “mad-cow” disease?
No transmission of mad cow disease has ever been connected with the dairy industry, either in the U.S. or abroad. It is scientifically proven to the highest standards that neither milk or colostrum products can transmit BSE. Additionally, all farms are monitored and do not feed animal by-products, which are the only known sources of BSE.
17. I am a vegan. I don’t eat animal foods. Isn’t colostrum an animal food?
Strictly speaking, colostrum is an animal (dairy) food. However, even the strict vegan diet of India’s Hindu Rishis as included colostrum for thousands of years. In modern India, the milkman delivers colostrum to the wealthy. Even vegetarians are designed to be breast-fed at birth and are naturally meant to receive toward benefits of this remarkable substance.
18. How is StemForte® different from other supplements?
Lots of formulas on the market are herbal, or fruit extracts, that little to no scientific backing. The concept behind StemForte®, however, is not only the release of one’s own stem cells, but to show the viability of those stem cells that were activated. The NuVi Global website also contains information that shows the other activate substances found in the StemForte® formula – ingredients which other companies lack.
19. Does StemForte® contain iodine?
Most people think that all algae are a significant source of iodine, but the content of iodine is not significant. The Recommended Daily Allowance of iodine is 150 mcg. Our wakame and brown seaweed contain small amounts of iodine. For example, wakame powder extract: 28.45 mcg and Brown seaweed powder: 15.57 mcg per gram.
Marine algae and seaweed, by contrast, are significant sources of iodine. For example, one gram of kelp from the species Laminaria digitata contains approximately 5000 mcg of iodine. Iodized salt contains 100 mcg per gram, and one teaspoon of iodized salt contains 400 mcg of iodine. Other examples of foods that contain iodine include one slice of bread, which has approximately six mcg, and one medium egg, which has 14 mcg of iodine.
21. Can you take StemForte® if you are being treated by a health care practitioner for a specific ailment, or are taking medications of any kind?
As with any dietary supplement, we recommend that if you are being treated by a health care practitioner, or are taking medications of any kind, that you consult with your practitioner prior to taking StemForte®.
22. Why does the label advise people on anticoagulants to consult their physician prior to taking StemForte®, and what information will their physician need?
The issue pertains to the anticoagulant medication called Coumadin™, or Warfarin. People on Warfarin are usually advised by their prescribing physician to pay attention to the amount of Vitamin K in their diet. Like many foods, StemForte® contains naturally occurring vitamin K. So, taking StemForte® would be similar to eating a food with vitamin K such as broccoli or spinach. The Recommended Daily Allowance of vitamin K is 80 mcgs.
Let the physician know that 1 capsule of StemForte® has approximately 17.45 mcgs of vitamin K, and the suggested dosage (3) capsules is 52.35 mcg, which is approximately 3/4, the RDA of vitamin K.
To give an example of comparisons to other foods, one cup of broccoli, raw, and chopped has “about” 110% of the RDA (or 88 mcg) of vitamin K. A ½ cup of spinach, fresh, and boiled has about 555% of the RDA (or 444 mcgs) of vitamin K.
Remember to always consult your health care provider for any questions or concerns.
24. Can StemForte® be taken if you have health conditions?
StemForte® supports the natural release of our stem cells. There is a theoretical possibility that it may be contraindicated in people having a disease of the bone marrow. This is, however, only theoretical, and is not based on any known ill effect(s). People should consult their health care practitioner prior to taking StemForte®.